App Note
Very low mass isotope data collection with the Nu Vitesse, measurement of microplastic particles
Time-of-flight ICP-MS is recognised as a simultaneous elemental analysis technique but the intrinsic qualities of a time-of-flight mass spectrum mean that sensitivity for very light masses is much lower than for heavier masses. The use of a multipole device in the reaction cell to remove interferences also introduces a mass bias in the instrument response which is partially overcome in the Nu Vitesse by the use of an axial field gradient across the reaction cell. The pressurising of the cell and required RF field needed to obtain broad band transmission across the mass range generally means that sensitivities below 23Na are sometimes too low to be useful in full mass range spectra. This note will show how very low mass data can be obtained with specific tuning conditions and how this benefits certain applications such as the analysis of microplastics.
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